Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging
نویسندگان
چکیده
منابع مشابه
Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging.
The emergence and spread of antibiotic-resistant bacteria are aggravated by incorrect prescription and use of antibiotics. A core problem is that there is no sufficiently fast diagnostic test to guide correct antibiotic prescription at the point of care. Here, we investigate if it is possible to develop a point-of-care susceptibility test for urinary tract infection, a disease that 100 million ...
متن کاملAntibiotic Susceptibility Testing
12.2 TERMINOLOGY Selectivity All Clinically effective antimicrobial agents exhibit selective toxicity towards the bacterium rather than the host. It is this characteristic that distinguishes antibiotics from disinfectants. The basis for selectivity will vary depending on the particular antibiotic. When selectivity is high the antibiotics are normally non toxic. However, even highly selective an...
متن کاملAntibiotic susceptibility testing by a standardized single disk method.
In the words of the authors, the paper by A. W. Bauer et al., from the University of Washington in Seattle, on a standardized single-disk method for antibiotic susceptibility testing “. . . consolidate(s) and update(s) previous descriptions of the method and provide(s) a concise outline for its performance and interpretation.” Clinical microbiologists were relieved that finally a disk diffusion...
متن کاملAntibiotic treatment and susceptibility testing.
T he concept of attacking invading microorganisms without harming the host was first introduced by Paul Ehrlich. In 1910 he discovered ‘‘salvarsan’’, which he announced as a magic bullet for the treatment of syphilis. Penicillin, produced by the fungus, Penicillium notatum, was first discovered by Alexander Fleming in 1928, purified by Florey and Chain in 1940, and shown to have wide applicabil...
متن کاملFast Antibiotic Susceptibility Testing (FASTest) based on single cell growth rate measurements
Fast Antibiotic Susceptibility Testing (FASTest) based on single cell growth rate measurements. Short Title: Fast Antibiotic Susceptibility Testing (FASTest) Özden Baltekin , Alexis Boucharin , Dan I. Andersson , Johan Elf a,1 a Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, SE-751 24 Uppsala, Sweden; and b Department of Medical Biochemistry and Micro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2017
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1708558114